CHLORTHALIDONE

CHLORTHALIDONE

Stock Code: 3574100
Manufacturer Part No: SML0591-5MG
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Biochem/physiol Actions


Chlorthalidone is a thiazide-like diuretic, an inhibitor of the Na+-Cl- cotransporter. Chlorthalidone inhibits sodium ion transport across the renal tubular epithelium increasing the delivery of sodium to the distal renal tubule and indirectly increasing potassium excretion via the sodium-potassium exchange mechanism. Chlorthalidone also promotes Ca++ reabsorption by an unknown mechanism. Several recent comparison studies inidcate that chlorthalidone may be a better drug in preventing cardiovascular events than hydrochlorothiazide.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyJIVPVXMEBJLZRO-UHFFFAOYSA-N
InChI1S/C14H11ClN2O4S/c15-11-6-5-8(7-12(11)22(16,20)21)14(19)10-4-2-1-3-9(10)13(18)17-14/h1-7,19H,(H,17,18)(H2,16,20,21)
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityDMSO: 5 mg/mL, clear (warmed)
Formpowder
Assay≥98% (HPLC)

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