5-Sulfosalicylic acid dihydrate, for electrophoresis, >=99%

Stock Code: 3577453
Manufacturer Part No: S3147-100G
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Analysis Note


Tested for use in fixing solutions for PAGE, SDS-PAGE and IEF.


Application


5-Sulfosalicylic acid dihydrate may be employed for the quantification of doxorubicin derived from PEGylated liposomal doxorubicin (Doxil) and its major metabolite in human plasma by HPLC. It may be used in the preparation of poly[[tris(di-2-pyridylamine)tris([?]-5-sulfonatosalicylato)tricopper(II)] trihydrate].


5-Sulfosalicylic acid (3.5%) in 12% trichloroacetic acid is commonly used as a fixing solution for proteins in agarose and polyacrylamide gels.


General description


5-Sulfosalicylic acid is a strong acid capable of protonating water. It forms a new theophylline complex, which was investigated by X-ray photoelectron spectroscopy (XPS). It forms 1:1 proton-transfer compounds with the ortho-substituted monocyclic heteroaromatic Lewis bases. Their crystal structures have been studied.


Packaging


100, 500 g in poly bottle

Pack100G
mp105-110 °C (lit.)
InChI keyBHDKTFQBRFWJKR-UHFFFAOYSA-N
InChI1S/C7H6O6S.2H2O/c8-6-2-1-4(14(11,12)13)3-5(6)7(9)10;;/h1-3,8H,(H,9,10)(H,11,12,13);2*1H2
ManufacturerSIGMA-ALDRICH
Impurities≤0.02% Insoluble matter, ≤0.05% Salicylic Acid
Formpowder or crystals
Assay≥99%

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