Thrombin Receptor Activator Peptide 6, , >95% (HPLC)

Thrombin Receptor Activator Peptide 6, , >95% (HPLC)

Stock Code: 3593715
Manufacturer Part No: T1573-5MG
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Amino Acid Sequence

Ser-Phe-Leu-Leu-Arg-Asn

Application

Thrombin Receptor Activator Peptide 6 has been used to activate platelets in vitro. It has also been used to downregulate hippo signaling and increase nuclear yes-associated protein (YAP).

Biochem/physiol Actions

Hexapeptide fragment of the thrombin receptor (residues 42-47). Shown to activate the thrombin receptor and cause platelet aggregation (EC50 = 0.8 µM).

General description

Thrombin Receptor Activator Peptide 6 (TRAP-6) protects astrocytes from cell death, which is associated with hypoglycemia. TRAP-6 induced aggregation and impaired adhesion to collagen under flow conditions.

Other Notes

Lyophilized from 0.1% TFA in H2O

Packaging

5 mg in glass bottle

Quality Level200
InChI keyHAGOWCONESKMDW-FRSCJGFNSA-N
InChI1S/C34H56N10O9/c1-18(2)13-23(30(49)40-22(11-8-12-39-34(37)38)29(48)44-26(33(52)53)16-27(36)46)42-31(50)24(14-19(3)4)43-32(51)25(41-28(47)21(35)17-45)15-20-9-6-
ManufacturerSIGMA-ALDRICH
Solubility0.1% TFA: soluble, water: soluble
Formlyophilized
Assay>95% (HPLC)

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