IRAK3, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, >=70% (SDS-PAGE),

IRAK3, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, >=70% (SDS-PAGE),

Stock Code: 3593568
Manufacturer Part No: SRP5353-20UG
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General description

IRAK3 or interleukin-1 receptor-associated kinase 3 is a member of the interleukin-1 receptor-associated kinase protein family which is essential components of the Toll/IL-R immune signal transduction pathways. IRAK3 is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. IRAKM mediates critical aspects of innate immunity that result in an immunocompromised state during sepsis. Mutations in IRAK3 are associated with a susceptibility to asthma.

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

Preparation Note

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.

ManufacturerSIGMA-ALDRICH
Storage Temp.−70°C
Formbuffered aqueous glycerol solution
Assay≥70% (SDS-PAGE)

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