DYRK2, active, GST tagged human, PRECISIO, recombinant, expressed in E. coli, >=70% (SDS-PAGE), buff

DYRK2, active, GST tagged human, PRECISIO, recombinant, expressed in E. coli, >=70% (SDS-PAGE), buff

Stock Code: 3593545
Manufacturer Part No: SRP5326-10UG
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General description

DYRK2 (also known as dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2) belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development and is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 expressed in E. coli demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. DYRK2 also regulates p53 to induce apoptosis in response to DNA damage.

Legal Information

PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

Preparation Note

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.

ManufacturerSIGMA-ALDRICH
Product LinePRECISIO®
Formbuffered aqueous glycerol solution
Assay≥70% (SDS-PAGE)

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