HDAC9, active, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, >=70% (SD

HDAC9, active, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, >=70% (SD

Stock Code: 3593496
Manufacturer Part No: SRP5268-10UG
Order Now for 7 day delivery
Click Add to Quote for price and delivery
Quantity: - +

General description

HDAC9 or MIRT belongs to the histone deacetylase /acuc/apha family and is a component of the histone deacetylase complex. HDAC9 gene is orthologous to the Xenopus and mouse MITR genes (MEF2-interacting transcription repressor). HDAC9 represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. HDAC9 is a calcium-sensitive transcriptional repressor of MEF2. Binding of calmodulin to HDAC9 leads to its dissociation from MEF2, relieving MEF2 from the transcriptional repression. HDAC9 is a signal-responsive transcriptional repressor in mouse skeletal muscle that is downregulated upon denervation.

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

Preparation Note

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.

ManufacturerSIGMA-ALDRICH
Formbuffered aqueous glycerol solution
Assay≥70% (SDS-PAGE)

There are no downloads for this product.