KAT2A (GCN5), active, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, >=

KAT2A (GCN5), active, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, >=

Stock Code: 3593493
Manufacturer Part No: SRP5264-10UG
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General description

KAT2A (K (lysine) acetyltransferase 2A) is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator which functions as a repressor of NF-kappa-B by promoting ubiquitination of the NF-kappa-B subunit RELA in a HAT-independent manner. KAT2A control chromosome stability by coordinating the ATR checkpoint and double-strand break processing with autophagy. KAT2A acetyltransferases have homologous sequences and enzymatic activities which are important for recognition of nucleosomal substrates.

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

Preparation Note

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.

ManufacturerSIGMA-ALDRICH
Formbuffered aqueous glycerol solution
Assay≥70% (SDS-PAGE)

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