ALK3 (187-end), active, GST tagged human, PRECISIO Kinase, recombinant, expressed in baculovirus inf

Stock Code: 3593286
Manufacturer Part No: SRP5002-10UG

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Descriptions

General description

BMPR1A (also known as bone morphogenetic protein receptor 1A) is a member of the transmembrane serine/threonine kinase family that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A act as a minor susceptibility gene for PTEN-mutation-negative Cowden syndrome. BMPR1A regulates the PTEN protein levels by decreasing PTEN′s association with the degradative pathway. BMPR1A trafficking plays a significant role in FOP pathogenesis and is also involved in human T-cell differentiation.

Legal Information

PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC

Physical form

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Preparation Note

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles