BRG1, wild type human, recombinant, expressed in insect cells, >=80% (SDS-PAGE)

BRG1, wild type human, recombinant, expressed in insect cells, >=80% (SDS-PAGE)

Stock Code: 3592881
Manufacturer Part No: SRP2036-5UG
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Biochem/physiol Actions

The wild type human brahma-related gene 1 (Brg1) encodes a protein of 1,647 amino acids that contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription regulation. BRG1 is an essential component of the SWI/SNF chromatin remodeling complexes and implicated in multiple functions through its interaction with different proteins, including the tumor suppressor protein pRb, serine-threonine kinase LKB1, and other transcription factors. Although Brg1 is involved in chromatin remodeling as a complex with other SWI/SNF proteins, purified BRG1 itself is capable of remodeling mono-nucleosomes and nucleosomal arrays in vitro. Mutations of Brg1 have been found in multiple tumor cell lines.

Physical form

Clear and colorless frozen liquid solution

Preparation Note

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

Colourclear, colorless
ManufacturerSIGMA-ALDRICH
Formfrozen liquid
Assay≥80% (SDS-PAGE)

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