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HDAC Substrate 1, fluorogenic, >=90% (HPLC)

Stock Code: 3592694
Manufacturer Part No: SRP0305-500NMOL

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Descriptions

Application

Study enzyme kinetics, and screen small molecule inhibitors for drug discovery and HTS applications.

General description

A fluorogenic, acetylated peptide substrate for HDAC′s. Based on residues 379-382 of p53, Arg-His-Lys-Lys, Ac, a site of regulatory acetylation by the p300 and CBP acetyltransferases, lysines 381, 382, 1-3, it is a suitable substrate for HDAC2, HDAC3, and HDAC6 tested so far.

Physical form

Supplied as a 5 mM solution in DMSO.

Specifications

Manufacturer	SIGMA-ALDRICH
Storage Temp.	−70°C
Form	aqueous solution
Assay	≥90% (HPLC)

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