MMP 2 / MMP 9 Substrate, >=97% (HPLC)

Stock Code: 3592468
Manufacturer Part No: SCP0191-5MG
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Amino Acid Sequence

DNP-Pro-Leu-Gly-Met-Trp-Ser-Arg

Application

Matrix metalloproteinases (MMP) are a family of zinc-dependent endopeptidases that degrade matrix proteins. MMPs include collagenases, gelatinases, matrilysins, enamelysins, metalloelastases, stromelysins and other structural protein and receptor lysins. The activity of these enzymes is selectively inhibited or measured by appropriately labeled peptides. DNP-Pro-Leu-Gly-Met-Trp-Ser-Arg (DNP-PLGMWSR), Dnp-Pro-Leu-Gly-Leu-Trp-Ala-D-Arg-NH2 (DNP-PLGLWA-D-R-NH2), Dnp-Pro-Gln-Gly-Ile-Ala-Gly-Gln-D-Arg-OH (DNP-PQGIAGQ-D-R-OH) and MOCAc [(7-methoxy coumarin-4-yl) acetyl]-RPKPYANvaWMK(Dnp[2,4-dinitrophenyl])-NH(2) are substrates for matrix metalloproteinase 2 and matrix metalloproteinase 9.

ManufacturerSIGMA-ALDRICH
CompositionPeptide Content, ≥78%
Storage Temp.−20°C
Formlyophilized
Assay≥95% (HPLC)

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