Granzyme B Substrate, >=98% (HPLC)

Granzyme B Substrate, >=98% (HPLC)

Stock Code: 3592432
Manufacturer Part No: SCP0158-5MG
Order Now for 7 day delivery
Click Add to Quote for price and delivery
Quantity: - +

Amino Acid Sequence

Ac-Ile-Glu-Pro-Asp-AMC

Application

Granzyme B Substrate (Ac-IEPD-AMC) is a fluorogenic substrate for the detection and assay of caspase 8 and granzyme B which is involved in the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.

Biochem/physiol Actions

Granzymes belongs to serine proteinase family enzymes and it localizes along with perforin in granules. It is predominant in cytotoxic T cells. Granzyme B induces caspases dependent and independent cell death. It possesses specific cleavage action at aspartate residue in the substrate.

ManufacturerSIGMA-ALDRICH
CompositionPeptide Content, ≥85%
Storage Temp.−20°C
Formlyophilized
Assay≥95% (HPLC)

There are no downloads for this product.