Src human, >=90% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered a

Stock Code: 3592200
Manufacturer Part No: S5439-10UG
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Application

Human Src has been used to study the kinetics of Src entrapped in a series of different sol-gel derived materials.

Biochem/physiol Actions

SRC proto-oncogene, non-receptor tyrosine kinase (SRC) phosphorylates membrane proteins and nucleoproteins and activates various intracellular signaling cascades. It has been associated with a number of human malignancies and cancers.

General description

SRC proto-oncogene, non-receptor tyrosine kinase (SRC) belongs to the family of non-receptor tyrosine kinases. It contains an amino-terminal domain, conserved Src-homology domains (SH2 and SH3), a tyrosine kinase domain and the carboxyl-terminus. The gene encoding this protein is localized on human chromosome 20q11.23.

Physical form

Solution in 50?mM Tris pH?7.5, 0.05?mM EDTA, 1?mM DTT, 100?mM NaCl, 0.05% NP-40, and 50% glycerol.

Unit Definition

One unit will phosphorylate one nmole of poly(Gly:Tyr) 4:1 per minute at pH 7.5 at 30°C.

Quality Level200
ManufacturerSIGMA-ALDRICH
Formbuffered aqueous glycerol solution
Assay≥80% (SDS-PAGE)

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