RS 102895 hydrochloride, >=98% (HPLC), powder

RS 102895 hydrochloride, >=98% (HPLC), powder

Stock Code: 3592064
Manufacturer Part No: R1903-5MG
Order Now for 7 day delivery
Click Add to Quote for price and delivery
Quantity: - +

Application

RS 102895 hydrochloride has been used in bromodeoxyuridine (5-bromo-2?-deoxyuridine, BrdU) cell proliferation assay to study effect of IL33 (interleukin 33) on decidual stromal cell proliferation in present of the antagonist and to study the effects of antagonists on the accumulation of bone marrow-derived microglia.

Biochem/physiol Actions

RS 102895 hydrochloride has a high affinity to the ? subunit of the C-C motif chemokine receptor 2 (CCR2) and binds specifically to it. This results in the inhibition of CCR2 signaling. It also suppresses monocyte recruitment. Hence, RS 102895 may be useful for obstructing the immune suppressive effects of monocytes during early vaccine responses.

General description

RS 102895 hydrochloride is a small molecule antagonist of C-C motif chemokine receptor 2 (CCR2) which belongs to the spiropiperidine (SP) class.

Packaging

5 mg in glass bottle

Colourwhite
Quality Level100
InChI keyKRRISOFSWVKYBF-UHFFFAOYSA-N
InChI1S/C21H21F3N2O2.ClH/c22-21(23,24)16-7-5-15(6-8-16)9-12-26-13-10-20(11-14-26)17-3-1-2-4-18(17)25-19(27)28-20;/h1-8H,9-14H2,(H,25,27);1H
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥98% (HPLC)

There are no downloads for this product.