Protein kinase A inhibitor fragment 14-22, myristoylated trifluoroacetate salt has been used in cell culture for pharmaceutical inhibition and activation studies.
Biochem/physiol Actions
Mutations in the gene encoding protein kinase cAMP-activated catalytic subunit-? (PRKACA) have been associated with Cushing’;s syndrome.
Cell permeable cAMP-dependent protein kinase (PKA) inhibitor
General description
Protein kinase A inhibitor fragment 14-22, myristoylated trifluoroacetate salt inhibits the protein kinase cAMP-activated catalytic subunit-? (PRKACA). The gene encoding it is localized on human chromosome 19p13.1.