Protein kinase A inhibitor fragment 5-24 amide trifluoroacetate salt, >=95% (HPLC), lyophilized powd

Protein kinase A inhibitor fragment 5-24 amide trifluoroacetate salt, >=95% (HPLC), lyophilized powd

Stock Code: 3592027
Manufacturer Part No: P7739-1MG
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Amino Acid Sequence

Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-His-Asp-NH2

Biochem/physiol Actions

Binds to the catalytic subunit of protein kinase A (PKA), mimicking the protein substrate

General description

Protein kinase A inhibitor fragment inhibits the protein kinase cAMP-activated catalytic subunit alpha (PRKACA). The gene encoding it is localized on human chromosome 19p13.1. Mutations in the gene encoding protein kinase cAMP-activated catalytic subunit ? (PRKACA) have been associated with Cushing’;s syndrome.

Packaging

1 mg in glass bottle

Quality Level200
InChI keyCJBPFVMGYBOAOJ-AYVQDJQPSA-N
InChI1S/C94H149N33O30.C2HF3O2/c1-11-42(3)70(125-86(152)59(31-50-19-14-13-15-20-50)119-85(151)62(36-68(138)139)118-75(141)44(5)111-82(148)58(32-51-24-26-53(132)27-25
ManufacturerSIGMA-ALDRICH
CompositionPeptide content, ~75%
Formlyophilized powder
Assay≥95% (HPLC)

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