Protein Kinase G II from rat, , >90% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf9

Protein Kinase G II from rat, , >90% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf9

Stock Code: 3591982
Manufacturer Part No: P2363-5UG
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Biochem/physiol Actions

Protein kinase, cGMP-dependent, type II (PRKG2) is implicated in the regulation of intestinal fluid balance in man. The encoded protein plays an essential role in proliferative to hypertrophic transition of growth plate chondrocytes during endochondral ossification. Loss of PRKG2 function is associated with the development of renal cysts, intellectual disability and speech defect. In rodent and bovine models, deletion of the gene leads to dwarfism.

General description

Protein kinase, cGMP-dependent, type II (PRKG2), also known as type II cGMP-dependent protein kinase (cGK), is encoded by the gene mapped to human chromosome 4q13.1–q21.1.

Unit Definition

One unit will phosphorylate one µmole of VASPtide (RRKVSKQE) per minute at pH 7.4

Quality Level200
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
Formsolution
Assay>90% (SDS-PAGE)

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