[beta-Mercapto-beta,beta-cyclopentamethylenepropionyl1, O-Me-Tyr2, Orn8]-Oxytocin, >=93% (HPLC), sol

Stock Code: 3591924
Manufacturer Part No: O6887-1MG

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Descriptions

Amino Acid Sequence

β-Mercapto-β,β-Cyclopentamethylenepropionyl-MeTyr-Ile-Gln-Asn-Cys-Pro-Orn-Gly-NH2 [Disulfide Bridge: 1-6]

Application

[?-Mercapto-?,?-cyclopentamethylenepropionyl1, O-Me-Tyr2, Orn8]-Oxytocin has been used as an oxytocin receptor antagonist:to study the influence of blockading the oxytocin receptors in the anterior cingulate cortex on helping behavior to determine the receptors that mediate vasopressin-stimulated anion secretion across cultured porcine vas deferens epithelial cell monolayers to study the influence of oxytocin receptors inhibition on intravenous and in situ oxytocin effects on the urinary bladder and cardiovascular activities in sham rats

Biochem/physiol Actions

[?-Mercapto-?,?-cyclopentamethylenepropionyl1, O-Me-Tyr2, Orn8]-also acts as an arginine vasopressin receptor 1A (AVPR1A) antagonist.

Potent oxytocin antagonist.

Specifications

Quality Level	200
InChI key	ZWVZXPFUQHTUKV-SZQHDTAUSA-N
InChI	1S/C48H74N12O12S2/c1-4-27(2)40-46(70)56-31(16-17-36(50)61)42(66)57-33(23-37(51)62)43(67)58-34(47(71)60-21-9-11-35(60)45(69)55-30(10-8-20-49)41(65)53-25-38(52)6
Manufacturer	SIGMA-ALDRICH
Storage Temp.	−20°C
Form	solid
Assay	≥93% (HPLC)