Nicotinic acid, meets USP testing specifications

Nicotinic acid, meets USP testing specifications

Stock Code: 3591866
Manufacturer Part No: N5410-100G
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Application

Nicotinic acid has been used as an antioxidant to evaluate its protective functionality in colon LoVo cell lines against doxorubicin induced cytotoxicity.

Biochem/physiol Actions

Nicotinic modulates lipid metabolism and may be useful in treating dyslipidemia. It is an antioxidant and acts as a coenzyme in the form of nicotinamide adenine nucleotides. Deficiency of niacin leads to enhanced lipid peroxidation and is also implicated in Crohn?s disease Deficiency also impacts DNA repair and also leads to skin and gastrointestinal disorder, pellagra. Nicotinic acid reduces the low-density lipoprotein (LDL) synthesis and improves high-density lipoprotein (HDL) levels.

General description

Nicotinic acid, also referred to as niacin or as vitamin B3, is a water-soluble vitamin. Nicotinic acid is synthesized from the amino acid tryptophan and is present majorly in peanuts, fish and lean meat.

Colourwhite
InChI keyPVNIIMVLHYAWGP-UHFFFAOYSA-N
ManufacturerSIGMA-ALDRICH
Agencymeets USP testing specifications, USP/NF
Formpowder
Assay99.0-101.0% dry basis

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