Acetyl-[Nle4, Asp5, D-2-Nal7, Lys10]-cyclo-alpha-Melanocyte Stimulating Hormone Amide Fragment 4-10,

Acetyl-[Nle4, Asp5, D-2-Nal7, Lys10]-cyclo-alpha-Melanocyte Stimulating Hormone Amide Fragment 4-10,

Stock Code: 3591778
Manufacturer Part No: M4603-1MG
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Amino Acid Sequence

Ac-Nle-cyclo(Asp-His-Nal-Arg-Trp-Lys-NH2)

Biochem/physiol Actions

Screening analogs of the cyclic lactam melanocortin agonist MTII led to the identification of the agoutimimetic SHU9119. This compound shares pharmacological properties with the agouti peptide in that it is a potent antagonist of the melanocortin-4 receptor and a less potent antagonist of the melanocortin-3 receptor.

Quality Level200
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
Assay≥95% (HPLC)

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