Prolactin human, , recombinant, expressed in E. coli, lyophilized powder, BioReagent, cell culture t

Prolactin human, , recombinant, expressed in E. coli, lyophilized powder, BioReagent, cell culture t

Stock Code: 3591633
Manufacturer Part No: L4021-50UG
Order Now for 21 day delivery
Click Add to Quote for price and delivery
Quantity: - +

Analysis Note

The biological activity is assayed by proliferation of the rat lymphoma cell line, Nb2-11.

Application

Use in cell culture applications to study prolactin regulation of cell signaling and gene expression.

Biochem/physiol Actions

Prolactin is a neuroendocrine hormone. The prolactin receptor is a transmembrane glycoprotein that belongs to the cytokine hematopoietic receptor family. A large number of cells and organs express the receptor, including B cells, T cells, macrophages, monocytes, and neutrophils. Prolactin signal transduction involves the JAK/STAT families and the src kinase family. Induces lactation; inhibits secretion of gonadotropins; release is inhibited by dopamine.

Other Notes

Contains an N-terminal methionine not present in the natural product.

Physical form

Lyophilized from a solution in 10?mM phosphate and 50?mM sodium chloride, pH 8.0.

Reconstitution

It is recommended that sterile 4 mM HCl containing 1 mg/mL bovine serum albumin be added to the vial to prepare a stock solution of no less than 100 µg/mL.

ManufacturerSIGMA-ALDRICH
Further Info200 amino acid residue methionyl form of mature, recombinant human prolactin (amino acid residues 29-227).
Product LineBioReagent
Impuritiesendotoxin, tested
Formlyophilized powder
Assay>97% (SDS-PAGE)

There are no downloads for this product.