[D-Ala6]-LH-RH acetate salt hydrate, >=97% (HPLC)

[D-Ala6]-LH-RH acetate salt hydrate, >=97% (HPLC)

Stock Code: 3591617
Manufacturer Part No: L1898-5MG
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Amino Acid Sequence

Glp-His-Trp-Ser-Tyr-Ala-Leu-Arg-Pro-Gly-NH2

Application

[D-Ala6]-LH-RH acetate salt hydrate has been used to induce ovulation and to synchronize the reproductive cycle in Sprague-Dawley female rats.

Biochem/physiol Actions

Potent LH-RH agonist.

(D-Ala6)-LH-RH is a GnRH (gonadotropin-releasing hormone) agonist. GnRH, which is also referred to as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism.

Packaging

5 mg in glass bottle

Quality Level200
InChI keyKGUIXKYKIZMKMT-JGUOWLKQSA-N
InChI1S/C56H77N17O13.C2H4O2.H2O/c1-29(2)20-39(50(81)67-38(10-6-18-61-56(58)59)55(86)73-19-7-11-44(73)54(85)63-26-45(57)76)68-47(78)30(3)65-49(80)40(21-31-12-14-34(7
ManufacturerSIGMA-ALDRICH
CompositionPeptide content, ≥65%
Storage Temp.−20°C
Assay≥97% (HPLC)

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