Protein kinase C ? (PKC?) is involved in Ras signaling. In colonic epithelium, it is an important regulator of oncogenic Ras. Transgenic mice which are constitutively expressing PKC? are at high risk of carcinogen-mediated colon carcinogenesis.
General description
PKC? (protein kinase C ?) belongs to the protein kinase C family.
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Physical form
Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.