ITK (352-end), active, GST tagged human, PRECISIO Kinase, recombinant, expressed in baculovirus infe

ITK (352-end), active, GST tagged human, PRECISIO Kinase, recombinant, expressed in baculovirus infe

Stock Code: 3591550
Manufacturer Part No: I6160-10UG
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Biochem/physiol Actions

ITK (IL2-inducible T-cell kinase) is important for T-cell activation through the T-cell antigen receptor. Absence of ITK in T cells causes impairment in TCR (T cell receptor)-mediated actin polymerization, cell polarization and signaling events associated with cytoskeletal reorganization.

General description

ITK (IL2-inducible T-cell kinase) is a member of the Tec family of tyrosine kinases. ITK is expressed in T-cells.

Legal Information

PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

Quality Level200
ManufacturerSIGMA-ALDRICH
Product LinePRECISIO® Kinase
Formbuffered aqueous glycerol solution
Assay≥70% (SDS-PAGE)

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