The biological activity is measured by its ability to induce chemotaxis in IL-2 cultured human lymphocytes.
Biochem/physiol Actions
I-TAC (Interferon-inducible T-cell ? chemoattractant) is a chemokine which participates in recruitment of inflammatory cell. It binds to receptor CXCR3 (C-X-C motif chemokine receptor 3). I-TAC is associated with the severity of dengue.
Physical form
Lyophilized in 30% acetonitrile and 0.1% trifluoroacetic acid containing 1.25 mg of bovine serum albumin.