Interferon-gamma from mouse, >=98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder

Stock Code: 3591539
Manufacturer Part No: I4777-.1MG

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Descriptions

Analysis Note

The biological activity of recombinant mouse IFN-γ is measured by its ability to inhibit the proliferation of murine WEHI-279 cells.

Application

Interferon-? from mouse has been used:for in vitro stimulation of the BMDC (bone marrow derived dendritic cell), BMM (bone marrow-derived macrophages) and CD11c⁺ (CD11 antigen-like family member C) lung macrophagesfor stimulation of murine macrophages to induce the production of nitrite and nitrateto check CCAAT/enhancer binding protein ? (C/EBP?)-mediated changes in the expression of prostaglandin synthesis enzymes in neuroinflammation

Biochem/physiol Actions

Ifng (interferon-?) plays an important role in innate and adaptive immune responses, and helps in defense against bacterial infections, dimorphic yeast and some viral infections.

Physical form

Lyophilized from a 0.2 µm filtered buffered solution. Package size based on protein content.