Interleukin-4 from rat, recombinant, expressed in E. coli, lyophilized powder, suitable for cell cul

Stock Code: 3591531
Manufacturer Part No: I3650-5UG
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Analysis Note

The biological activity of recombinant rat IL-4 was measured by its ability to stimulate proliferation of rat splenocytes.

Biochem/physiol Actions

Interleukin-4 is a lymphokine with profound effects on the growth and differentiation of immunologically competent cells. IL-4 is also known as B cell stimulatory factor-1 (BSF-1), T cell growth factor-2 (TCGF-2) and mast-cell growth factor-2 (MCGF-2). Inhibits VEGF-induced and bFGF-induced angiogenesis. IL-4 is a complex glycoprotein released by a subset of activated T cells. Human and mouse IL-4 share 50% amino acid sequence homology, but their biological actions are species-specific.

Interleukin-4, a lymphokine with profound effects on the growth and differentiation of immunologically competent cells, inhibits VEGF-induced and bFGF-induced angiogenesis. Human and mouse IL-4 share 50% amino acid sequence identity, but their biological actions are species-specific.

Physical form

Lyophilized from a 0.2 µm filtered solution in phosphate buffered saline containing 0.25 mg bovine serum albumin.

Quality Level100
ManufacturerSIGMA-ALDRICH
Impuritiesendotoxin, tested
Formlyophilized powder
Assay≥97% (SDS-PAGE)

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