Interleukin-13 from mouse, >=97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder,

Stock Code: 3591513
Manufacturer Part No: I1896-5UG

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Descriptions

Biochem/physiol Actions

Interleukin-13 is a pleiotropic cytokine produced by activated Th2 cells in the mouse and human. IL-13 is secreted mainly as an unglycosylated protein of 132 amino acids with a molecular weight of 10,000 daltons. A 4.3kb DNA fragment of the mouse IL-13 gene was sequenced and occurs as a single copy mapping a chromosome 11. In the human, a 4.6 kb DNA segment of the IL-13 gene occurs as a single copy and maps to chromosome 5. IL-13 induces B cell proliferation and also induces IgE switching. The proliferative activity of human and mouse IL-13 products are tested in culture using the human erythroleukemic cell line TF-1.

Physical form

lyophilized from a 0.2 µm filtered solution in phosphate buffered saline (PBS), pH 7.4, with 50 µg bovine serum albumin (BSA) per 1 µg of cytokine