HIPK1 (156-555), active, GST tagged human, PRECISIO Kinase, recombinant, expressed in baculovirus in

Stock Code: 3591438
Manufacturer Part No: H3290-10UG

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Descriptions

Biochem/physiol Actions

HIPK1 (homeodomain-interacting protein kinase 1) is responsible for phosphorylation of homeodomain transcription factors. HIPK1 interacts with DAXX (death domain-associated protein 6) and decreases its transcriptional repression activity. It is up-regulated in breast cancer cell lines and is suggested to be involved in tumorigenesis, partly by serine phosphorylation of p53.

General description

HIPK1 (homeodomain-interacting protein kinase 1) is a serine/threonine protein kinase. It belongs to the HIPK family. The protein is present in the nucleus.

Legal Information

PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.