Growth Hormone Releasing Factor Fragment 1-29 amide human, >=97% (HPLC)

Growth Hormone Releasing Factor Fragment 1-29 amide human, >=97% (HPLC)

Stock Code: 3591348
Manufacturer Part No: G6771-1MG
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Amino Acid Sequence

Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2

Biochem/physiol Actions

Amidated GRF fragment that is equipotent to GRF in releasing somatotropin from anterior pituitary.

GHRH/GRH (growth hormone releasing hormone) is released from the hypothalamus from where it reaches the anterior pituitary and binds to its receptor, thus, eventually leading to the release of GH (growth hormone) into the plasma.

General description

GHRH/GRH (growth hormone releasing hormone) is an endocrine peptide hormone composed of 44 amino acids† It exists in two forms in the hypothalamus, namely GRH(1-44)-NH2 and GRH(1-40)-OH. However, the full biological functionality of this hormone resides in the first 29 amino acids itself. GRH(1-29)-NH2 is a C-terminal shortened peptide produced from GHRH.

Other Notes

Lyophilized from 0.1% TFA in H2O

Packaging

1 mg in glass bottle

Quality Level200
InChI keyWGWPRVFKDLAUQJ-MITYVQBRSA-N
InChI1S/C149H246N44O42S/c1-20-77(13)116(191-122(211)81(17)168-132(221)104(66-113(204)205)178-121(210)79(15)167-123(212)88(152)62-84-39-43-86(198)44-40-84)145(234)18
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
Assay≥97% (HPLC)

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