Glypican 3 human, recombinant, expressed in NSO cells

Stock Code: 3591282
Manufacturer Part No: G1921-50UG

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Descriptions

Biochem/physiol Actions

Sulfate proteoglycan attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor. Regulates cell survival and inhibits cell proliferation during normal development. Potential use as marker for early disease detection.

General description

Glypican-3, a cell surface protein, is highly expressed in hepatocellular carcinoma (HCC) and few other human cancers including melanoma. It is a heparan sulfate proteoglycan and is present on the cell surface. Under non-reducing conditions in SDS-PAGE, the glycanated glypican 3 appears as a smear with an apparent molecular mass of 60 - 100 kDa†

Physical form

Lyophilized from a 0.2 µm filtered solution in PBS containing 50 µg of bovine serum albumin per 1 µg of cytokine.