GR 64349, , >96%

Stock Code: 3591261
Manufacturer Part No: G113-1MG

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Descriptions

Amino Acid Sequence

Lys-Asp-Ser-Phe-Val-Gly-R-γ-lactam-Leu-Met-NH2

Biochem/physiol Actions

GR 64349 peptide acts as an agonist of neurokinin (NK₂) receptor, which leads to reduced NK₂ response to kainate and AMPA (?-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), but not to NMDA (N-methyl-D-aspartate).

General description

Neurokinin (NK) receptors are acted upon by tachykinins or neurokinins namely, NKA and NKB. These are endogenous ligands. An exogenous agonist/ligand for NK₂ is GR 64349 peptide.

Packaging

1 mg in glass bottle

Specifications

Quality Level	200
InChI key	HVUNRXRFMQDMBO-NOJSRKIXSA-N
InChI	1S/C42H68N10O11S/c1-23(2)19-32(40(61)46-27(35(45)56)15-18-64-5)52-17-14-28(42(52)63)47-41(62)34(24(3)4)51-38(59)29(20-25-11-7-6-8-12-25)49-39(60)31(22-53)50-37
Manufacturer	SIGMA-ALDRICH
Storage Temp.	−20°C
Assay	>96%