ERK2, active, GST tagged human, recombinant, expressed in E. coli, PRECISIO Kinase, >=70% (SDS-PAGE)

ERK2, active, GST tagged human, recombinant, expressed in E. coli, PRECISIO Kinase, >=70% (SDS-PAGE)

Stock Code: 3591111
Manufacturer Part No: E1283-10UG
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Biochem/physiol Actions

ERK2 is a protein serine/threonine kinase that is a member of the extracellular signal-regulated kinases (ERKs) which are activated in response to numerous growth factors and cytokines. Activation of ERK2 requires both tyrosine and threonine phosphorylation that is mediated by MEK. ERK2 is ubiquitously distributed in tissues with the highest expression in heart, brain and spinal cord. Activated ERK2 translocates into the nucleus where it phosphorylates various transcription factors (e.g., Elk-1, c-Myc, c-Jun, c-Fos, and C/EBP beta).

Legal Information

PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

Quality Level200
ManufacturerSIGMA-ALDRICH
Product LinePRECISIO® Kinase
Formbuffered aqueous glycerol solution
Assay≥70% (SDS-PAGE)

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