Ecarin from Echis carinatus venom, prothrombin activator

Ecarin from Echis carinatus venom, prothrombin activator

Stock Code: 3591101
Manufacturer Part No: E0504-1VL
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Application

Ecarin activity is the principal behind the Ecarin Clotting Time (ECT) assay, which is used to assess antithrombotic effect and thrombin inhibition.

Ecarin from Echis carinatus venom is the primary reagent in the ecarin clotting time (ECT) test, which is used to monitor anticoagulation and thrombin inhibition. It has been used in studies to test the effectiveness of medications for the treatment of venous and arterial thromboembolism.

Biochem/physiol Actions

Prothrombin activator

Unit Definition

One unit will activate prothrombin to produce one unit of amidolytic activity at pH 8.4 at 37?°C. One amidolytic unit will hydrolyze 1.0 µmole of N-p-tosyl-Gly-Pro-Arg-p-nitroanilide per min at pH 8.4 at 37?°C.

Quality Level200
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C

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