Defensin HNP-2 human, >=95% (HPLC)

Stock Code: 3591070
Manufacturer Part No: D6790-25UG
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Amino Acid Sequence

Cys-Tyr-Cys-Arg-Ile-Pro-Ala-Cys-Ile-Ala-Gly-Glu-Arg-Arg-Tyr-Gly-Thr-Cys-Ile-Tyr-Gln-Gly-Arg-Leu-Trp-Ala-Phe-Cys-Cys [Disulfide Bridges: 1−29, 3−18, 8−28]

Biochem/physiol Actions

This is an endogenous antibiotic peptide and monocyte chemotactic peptide produced by human neutrophils. Defensins are a family of 3-4 kDa (29-34 amino acids) peptides found in the granules of mammalian phagocytes. The members of this famuly are variably arginine-rich and all share 6 conserved cysteine residues that participate in intramolecular disulfide bonds.

General description

Chemical structure: peptide

Quality Level200
InChI keyGRZXCHIIZXMEPJ-HTLKCAKFSA-N
InChI1S/C147H217N43O37S6/c1-13-73(6)114-139(222)168-76(9)118(201)163-63-110(196)170-96(48-50-113(199)200)127(210)172-92(31-22-52-159-145(152)153)125(208)171-93(32-2
ManufacturerSIGMA-ALDRICH
Formsolid
Assay≥95% (HPLC)

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