Cytochrome P450 human, 2E1 isozyme microsomes, with P450 Reductase and cytochrome b5, recombinant, e

Cytochrome P450 human, 2E1 isozyme microsomes, with P450 Reductase and cytochrome b5, recombinant, e

Stock Code: 3589924
Manufacturer Part No: C5740-1VL
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Analysis Note

Cytochrome c Reductase, b5, P450 content and p-Nitrophenol Hydroxylase activity reported on a lot-specific basis.

Application

Cytochrome P450 is a heterogeneous family of isozymes whose primary function is to oxidize small molecules both as a function of intermediary metabolism (e.g., fatty acids) and to detoxify exogenous compounds (drugs or toxins). Alterations in the renal formation of Cytochrome P450 metabolites from arachidonic acid may participate in the formation of hypertension. Therefore, they have been identified as candidate mediators in the development of this multifactorial disease.

Biochem/physiol Actions

Cytochrome P450 is a heterogeneous family of isozymes whose primary function is to oxidize small molecules, both as a function of intermediary metabolism (e.g., fatty acids) and to detoxify exogenous compounds (drugs or toxins). Some isoforms have narrow substrate specificity, while others are promiscuous.

Quality Level200
ManufacturerSIGMA-ALDRICH
Further Info1.0 nmole P450 2E1 per 0.5 ml vial
Formbuffered aqueous solution (100 mM potassium phosphate, pH 7.4)

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