Collagen from rabbit skin, Bornstein and Traub Type I, powder

Collagen from rabbit skin, Bornstein and Traub Type I, powder

Stock Code: 3589923
Manufacturer Part No: C5608-100MG
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Application

Collagen-type 1 may be used in research of Idiopathic pulmonary fibrosis (IPF). Robust expression of collagen-type 1 is one distinctive feature of IPF. Additionally, collagen-type 1 has been used in studies on the effect of endoplasmic reticulum (ER) stress from IPF on myofibroblastic differentiation of lung fibroblasts. Collage-type 1 soluble in acidic solution produces three dimensional scaffolding useful in bioengineering and cell culture applications where biomaterials are needed to replace native collagen extracellular matrices.Collagen Type I has been used as a scaffold for the growth in vitro of stem cells in a wide variety of biomaterial engineering studies.

General description

Collagen is classified into a number of structurally and genetically distinct types. We use the nomenclature proposed by Bornstein and Traub. Do not confuse Sigma type designations with recognized collagen classification types.

Preparation Note

Prepared with modification of Gallop, P.M.

Quality Level200
ManufacturerSIGMA-ALDRICH
Technique(s)cell culture - stem cell: suitable
Further Infoacid soluble
Storage Temp.2-8°C
Solubilityaqueous sodium acetate buffer: soluble (0.01-0.5M), aqueous acid: ≤10 mg/mL
Formpowder

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