Cytochrome P450 human, 1A1 Isozyme Microsomes, with P450 Reductase, recombinant, expressed in baculo

Stock Code: 3589877
Manufacturer Part No: C3735-1VL

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Descriptions

Biochem/physiol Actions

Cytochrome P450 is a heterogeneous family of isozymes whose primary function is to oxidize small molecules, both as a function of intermediary metabolism (e.g., fatty acids) and to detoxify exogenous compounds (drugs or toxins). Some isoforms have narrow substrate specificity, while others are promiscuous.

The CYP1A1 isoform catalyzes 7-deethylation of ethoxyresorufin.

Physical form

Solution in 100 mM potassium phosphate buffer, pH 7.4.

Preparation Note

Microsomes containing human CYP1A1 and recombinant human NADPH-P450 reductase.