Cholecystokinin (CCK) Fragment 26-33 Amide, Non-sulfated, >=95% (HPLC), powder

Cholecystokinin (CCK) Fragment 26-33 Amide, Non-sulfated, >=95% (HPLC), powder

Stock Code: 3589843
Manufacturer Part No: C2901-1MG
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Amino Acid Sequence

Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2

Application

Cholecystokinin (CCK) Fragment 26-33 Amide, Non-sulfated has been used in the specificity testing against gastrin and pepsinogen I proteins.

Biochem/physiol Actions

Biologically inactive form of CCK-8; CCKB/gastrin receptor agonist that has no activity at the CCKA receptor.

Cholecystokinin (CCK) is a 115 amino acid preprohormone and a neurotransmitter. It exists in many isoforms. The octapeptide of CCK (CCK-8S) is the most abundant form. CCK is mapped to human chromosome 3p22.1. CCK interacts with receptors of the gastrointestinal tract and nervous system. Polymorphisms in the CCK is implicated in hallucinations in patients with Parkinson?s disease. CCK plays a key role in the activation of the calcineurin-regulated nuclear factor of activated T-cells (NFATs).

Quality Level200
InChI keyOIXQINQYMGNCII-UHFFFAOYSA-N
InChI1S/C49H62N10O13S2/c1-73-18-16-34(55-47(70)37(21-28-12-14-30(60)15-13-28)58-44(67)32(50)23-41(62)63)45(68)53-26-40(61)54-38(22-29-25-52-33-11-7-6-10-31(29)33)48
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
Formpowder
Assay≥95% (HPLC)

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