CAMK2gamma, active, GST tagged human, PRECISIO Kinase, recombinant, expressed in baculovirus infecte

Stock Code: 3589759
Manufacturer Part No: C0749-10UG

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Descriptions

Biochem/physiol Actions

CAMK2γ?is a?member of the CAMKII family which are ubiquitous serine/threonine protein kinases that have been implicated in diverse effects of hormones and neurotransmitters. CAMK2γ has?six alternatively spliced variants that encode six different isoforms. Some of these variants have been?identified in human tumors. Transgenic mice expressing a partially calcium-independent mutant form of CAMK2γ showed 1.5- to 2-fold increase in the thymus of?these mice, at least in part due to an increase in the life span of double-positive thymocytes. There was an increase in the number of T cells in the secondary lymphoid organs that had acquired an antigen-dependent memory phenotype.

Legal Information

PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.