Bone Morphogenetic Protein 4 human, , >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophili

Bone Morphogenetic Protein 4 human, , >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophili

Stock Code: 3589705
Manufacturer Part No: B2680-10UG
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Analysis Note

The biological activity is measured by its ability to induce alkaline phosphatase production by C2C12 myoblasts.

Biochem/physiol Actions

Cellular responses to BMP-4 are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. BMPs stimulate angiogenesis by inducing the production of VEGF A by osteoblasts. Mature human and mouse BMP-4 demonstrates 98% and 100% homology, respectively, to mature rat BMP-4.

Physical form

Lyophilized from a 0.2 µm filtered solution in 30% acetonitrile and 0.1% trifluoroacetic acid containing 50 µg of bovine serum albumin per 1 µg of cytokine.

ManufacturerSIGMA-ALDRICH
Impurities﹤1 EU/mg Endotoxin level (LAL test)
Formlyophilized powder
Assay>95% (SDS-PAGE)

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