Application
MSDH is suitable is suitable to induce lysosomal membrane destabilization toinvestigate the mechanistic basis for Bax/Bak-mediated autophagic cell death.
Biochem/physiol Actions
O-methyl-serine-dodecylamidehydrochloride(MSDH) stimulatescell death. After apoptosis, it may activate procaspase 3-like proteases and cause partial lysosomal rupture.
General description
O-methyl-serine-dodecylamide hydrochloride (MSDH) is a synthetic lysosomotropicdetergent.
Packaging
5 mL Amber Glass Screw Cap Vial (850546P-25mg)
| Storage Temp. | −20°C |
|---|---|
| Form | powder |
| Assay | >99% (TLC) |
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