For research use only. Not for use in diagnostic procedures.Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
Sjoegren Syndrome Autoantigen 1 is an important cyclin-dependent kinase complexes inhibitor and prevents the G1 to S phase transition during cell cycle. It is regulated by ubiquitin-proteasome. The Sjoegren Syndrome Autoantigen 1 gene expression is downregulated in cancer and indicates poor prognosis.
General description
The SSSCA1 (Sjoegren syndrome/scleroderma autoantigen 1) gene codes for a cell cycle inhibitor, also called as p27. The SSSCA1 gene is mapped to human chromosome 11q13.1.
The antibody pair provided in this kit recognizes human SSSCA1.