For research use only. Not for use in diagnostic procedures.Rat Tumor Necrosis Factor ? ELISA Kit has been used to measure rat tumor necrosis-? (TNF-?) in cell lysate and tissue lysate.
Biochem/physiol Actions
Tumor necrosis factor-? (TNF-?) affects various cellular processes such as blood-brain barrier, inflammatory, thrombogenic, and vascular changes following brain damage. TNF-? expression is upregulated in various central nervous system disorders, including Alzheimer’;s disease, multiple sclerosis, Parkinson’;s disease, meningococcal meningitis and HIV infection. Elevated expression of TNF-? in brain and blood in response to lipopolysaccharide might increase brain stem thrombosis and hemorrhage and stroke sensitivity/risk in hypertensive rats. Tumor necrosis factor-? activates polymorphonuclear leukocyte NADPH oxidase, thereby facilitates development of systemic oxidative stres (OS), inflammation and hypertension in rats.
General description
The Rat TNF-α ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Rat TNF-α cell lysate and tissue lysate.
Immunogen
Recombinant Rat TNF-α
Other Notes
A sample Certificate of Analysis is available for this product.Please type the word samplein the text box provided for lot number.