Human IL-2 ELISA Kit, for serum, plasma, cell culture supernatant and urine

Stock Code: 3587585
Manufacturer Part No: RAB0286-1KT
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Application


Human IL-2 ELISA Kit has been used in the analysis of interleukins levels in human plasma.


Biochem/physiol Actions


IL-2 (interleukin 2) is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. It is a type I cytokine. IL-2/IL-2R (interleukin 2/IL-2 receptor) signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK (natural killer) cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. It is associated with recurrent oral ulcer, asthma and Mycoplasma pneumoniae infection in children. Absence of IL2 in mice causes fatal lymphoproliferative inflammatory disease (IL-2 deficiency syndrome). IL-2 signaling involves three pathways: phosphoinositol 3-kinase (PI3-K)/AKT, Ras-MAPK (mitogen activated protein kinase), and JAK-STAT (Janus kinase - signal transducers and activators of transcription) pathways.


General description


The Human IL-2 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human IL-2 in serum, plasma, cell culture supernatants and urine.


Immunogen


Recombinant Human IL-2


Other Notes


A sample Certificate of Analysis is available for this product.Please type the word sample in the text box provided for lot number.

ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C

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