Rat IL-1 beta ELISA Kit, for cell and tissue lysates

Stock Code: 3587578
Manufacturer Part No: RAB0278-1KT

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Descriptions

Application

For research use only. Not for use in diagnostic proceduresRat IL-1 ? ELISA Kit has been used to measure IL-1 ? levels .Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Pro-inflammatory cytokine IL-1 ? (IL1B), which is highly expressed on ?-adrenoreceptor in obese adipose tissues, is implicated in induction of uncoupling protein 1 (UCP1) expression via extracellular signal-regulated kinase (ERK) activation in adipocytes. Macrophage autophagy inhibits the production of inflammasome-dependent IL-1? and thereby it plays a vital role in reducing acute toxin-induced liver injury and death. In rats, IL-1? enhanced neurogenesis and plasticity of carotid bodies (CB) by triggering ERK1/2 activation. IL-1? plays a vital role in alteration of glomerular hemodynamics via stimulating the production of prostaglandin E2 (PGE2) in the mesangial cells.

General description

The Rat IL-1 β ELSA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Rat IL-1β cell lysate and tissue lysate.

Immunogen

Recombinant Rat IL-1 β

Other Notes

A sample Certificate of Analysis is available for this product.Please type the word sample in the text box provided for lot number.