Mouse IL-1 beta ELISA Kit, for cell and tissue lysates

Stock Code: 3587575
Manufacturer Part No: RAB0275-1KT

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Descriptions

Application

Mouse IL-1 ? ELISA Kit has been used to measure the concentration of interleukin 1 (IL)1-? in serum and bronchoalveolar lavage fluid (BALF) sample.

For research use only. Not for use in diagnostic procedures.Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Interleukin 1 ? (IL-1?) stimulates the production of endogenous 92 kDa gelatinase (matrix metalloproteinases 9 (MMP-9)) and tissue inhibitors of MMP (TIMP -1). It is a proinflammatory cytokine that induces various acute and chronic inflammation. Therefore, IL-1? can be considered as a potential therapeutic target for disease associated with fibrosis and tissue remodeling. IL-1? brings neutrophil and macrophage to the site of infection. Over expression of IL-1? in synovial fluid contributes to the pathogenesis of synovitis and degenerative changes of the cartilaginous tissue and bone of the temporomandibular joint. Mutations in IL-1? gene leads to renal manifestations and renal sequelae in Henoch-Schonlein purpura (HSP).

General description

The Mouse IL-1 β ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse IL-1 β cell lysate and tissue lysate.

Immunogen

Recombinant Mouse IL-1 β

Other Notes

A sample Certificate of Analysis is available for this product.Please type the word sample in the text box provided for lot number.