Human IL-1 beta ELISA Kit, for serum, plasma, cell culture supernatant and urine

Stock Code: 3587573
Manufacturer Part No: RAB0273-1KT

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Descriptions

Application

For research use only. Not for use in diagnostic procedures.Human IL-1 ? ELISA kit has been used to measure the concentration of interleukin 1? (IL-1 ?) in cell culture supernatants.

Biochem/physiol Actions

Interleukin 1? (IL-1 ?) is a proinflammatory cytokine, which is implicated in induction of various acute and chronic inflammation. Hence, IL1B can be considered as a potential therapeutic target for disease associated with fibrosis and tissue remodeling. IL-1? protein increases the production of endogenous 92kDa gelatinase (matrix metalloproteinases 9 (MMP-9)) and tissue inhibitors of MMP (TIMP -1). Elevated concentration of IL-1? in synovial fluid contributes to the pathogenesis of synovitis and degenerative changes of the cartilaginous tissue and bone of the temporomandibular joint. IL-1? brings neutrophil and macrophage to the site of infection. Mutations in IL-1? gene are linked with renal manifestations and renal sequelae in Henoch-Schönlein purpura (HSP).

General description

The Human IL-1 β ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human IL-1 β in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Human IL-1β

Other Notes

A sample Certificate of Analysis is available for this product.Please type the word sample in the text box provided for lot number.