Human IL-10 ELISA Kit, for serum, plasma, cell culture supernatant and urine

Stock Code: 3587546
Manufacturer Part No: RAB0244-1KT
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Application


For research use only. Not for use in diagnostic procedures.Human IL-10 ELISA kit has been used for determining the levels of IL-10 in cell culture supernatant.


Human IL-10 ELISA Kit has been used in enzyme-linked immunosorbent assay (ELISA) to detect interleukin-10 (IL-10) in the plasma of uremic patients undergoing hemodialysis (HD).


Biochem/physiol Actions


IL-10 (interleukin 10) is an anti-inflammatory cytokine. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNF (tumor necrosis factor)-?. Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Polymorphisms in the IL-10 gene are associated with higher risk of preeclampsia, ankylosing spondylitis, nasopharyngeal carcinoma and basal cell carcinoma. Polymorphism in IL-10 at -1082A/G is associated with diabetic nephropathy.


General description


Interleukin-10 (IL-10) is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells and B cells. Murine IL-10 is inactive on human cells. The gene encoding this protein is localized on human chromosome 1q31-32.


Immunogen


Recombinant Human IL-10


Other Notes


A sample Certificate of Analysis is available for this product.Please type the word sample in the text box provided for lot number.

ManufacturerSIGMA-ALDRICH
Technique(s)capture ELISA: suitable, ELISA: suitable
Storage Temp.−20°C

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