Mouse ICAM-1 ELISA Kit, for serum, plasma and cell culture supernatant

Stock Code: 3587522
Manufacturer Part No: RAB0220-1KT
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Application


For research use only. Not for use in diagnostic procedures.Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)


Biochem/physiol Actions


Intercellular adhesion molecule-1 (ICAM-1) is a member of immunoglobulin (Ig) superfamily. It is an inducible transmembrane glycoprotein. ICAM-1 mediates adhesion of circulating leukocytes to the endothelial membrane and blood vessel. ICAM-1 might cause atherosclerosis and the polymorphism in ICAM-1 has reduced risk to cardiovascular diseases. IL-6 induces the upregulation of ICAM-1 and leads to metastasis of osteosarcoma cells. ICAM-1 causes invasion and metastasis of breast cancer cells. ICAM-1 is an important receptor for rhinovirus and Haemophilus influenzae binding. Upregulation of ICAM-1 in the respiratory tract of chronic airway limitation patients increases the risk of respiratory infections.


General description


The Mouse ICAM-1 (Intercellular Adhesion Molecule-1) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme- linked immunosorbent assay for the quantitative measurement of mouse ICAM-1 in serum, plasma, cell culture supernatants and urine.


Immunogen


Recombinant Mouse ICAM1


Other Notes


A sample Certificate of Analysis is available for this product.Please type the word sample in the text box provided for lot number.

ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C

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